Publications

Nature Human Behavior: The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders
Nature Human Behavior: Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits
Nature Mental Health: Neurophysiological stratification of major depressive disorder by distinct trajectories
Nature Mental Health: The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression
Nature Mental Health: Personality traits and brain health: a large prospective cohort study
Nature Mental Health: Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia
Nature Aging: The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health
Molecular Psychiatry: Association of life course adiposity with risk of incident dementia: a prospective cohort study of 322,336 participants
Alzheimer’s Dement: Contribution of Alzheimer’s disease pathology to biological and clinical progression: A longitudinal study across two cohorts
eClinicalMedicine: Development of a novel dementia risk prediction model in the general population: A large, longitudinal, population-based machine-learning study

# Co-first author, * Corresponding author

2024

(*) C Fei, Z Li, J Ning,…,W Cheng, J Yu. Exome sequencing identifies genes associated with sleep-related traits. Nature Human Behavior (2024). [PDF]
(*) SD, Chen, J You, W Zhang,…, W Cheng, J Yu. The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders. Nature Human Behavior (2024). [PDF]
(*) B, Zhang, ET Rolls, X Wang,…, W Cheng, J Feng. Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment. Molecular Psychiatry (2024). [PDF]
(*) Z Li, Q Ma, Y Deng,…, J Feng, W Cheng. (2024). Irritable Bowel Syndrome is Associated with Brain Health by Neuroimaging, Behavioral, Biochemical, and Genetic Analyses. Biological psychiatry, (2024) S0006-3223(24)00027-1. [PDF]

2023

(*) J You, Y Guo, Y Zhang, …, J Feng, W Cheng, J Yu. Plasma proteomic profiles predict individual future health risk. Nature Communications, 14, 7817 [2023]. [PDF]
(*) YJ Ge, BS Wu, Y Zhang, …, W Cheng, J Yu. Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits. Nature Human Behavior, [2023]. [PDF]
(*) D Chen, X Wang, V Voon, …, TY Jia, W Cheng, J Feng. Neurophysiological stratification of major depressive disorder by distinct trajectories. Nature Mental Health, 1, 863–875 [2023]. [PDF]
(*) BS Wu, YR Zhang, Y Liu, …, W Cheng, J Yu. Polygenic Liability to Alzheimer’s Disease Is Associated with a Wide Range of Chronic Diseases: A Cohort Study of 312,305 Participants. Journal of Alzheimer’s Disease, 91(1):437-447 [2023]. [PDF]
(*) YJ Zhao, L Yang, BJ Sahakian, …, J Yu, J Feng, W Cheng. The brain structure, immunometabolic and genetic mechanisms underlying the association between lifestyle and depression. Nature Mental Health, [2023]. [PDF]
(*) YR Zhang, YT Deng, YZ Li, …, W Cheng, J Yu. Personality traits and brain health: a large prospective cohort study. Nature Mental Health, [2023]. [PDF]
(*) Y Jiang, J Wang, E Zhou, L Palaniyappan, …, W Cheng, J Feng, the ZIB Consortium. Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia. Nature Mental Health, [2023], 186–199. [PDF]
(*) C Shen, ET Rolls, ST Xiang, C Langley, BJ Sahakian, W Cheng, J Feng. Brain and molecular mechanisms underlying the nonlinear association between close friendships, mental health, and cognition in children. eLife, [2023], 12:e84072. [PDF]
(*) C Zhou, L Wang, W Cheng, …, J Feng, M Zhang. Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease. npj Parkinson’s Disease, [2023], 9, 111. [PDF]
(*) YJ Sun, BJ Sahakian, C Langley, …, W Cheng, J Feng. Early-initiated childhood reading for pleasure: associations with better cognitive performance, mental well-being and brain structure in young adolescence. Psychological Medicine, [2023], 1-15. [PDF]
(*) J You, Y Guo, J Kang, H Wang, M Yang, J Feng, J Yu, W Cheng. Development of machine learning-based models to predict 10-year risk of cardiovascular disease: a prospective cohort study. Stroke and Vascular Neurology, [2023]. [PDF]
(*) L Wang, C Zhou, W Zhang, M Zhang, W Cheng, J Feng. Association of Cortical and Subcortical Microstructure With Clinical Progression and Fluid Biomarkers in Patients With Parkinson Disease. Neurology, [2023], 101(3), e300-e310. [PDF]
(*) W Zhang, H Wang, K Kuo, L Wang, Y Li, J Yu, J Feng, W Cheng. Contribution of Alzheimer’s disease pathology to biological and clinical progression: A longitudinal study across two cohorts. Alzheimer’s Dementia, [2023], 1-11. [PDF]
(*) YN Ou, BS Wu, YJ Ge, Y Zhang, YC Jiang, K Kuo, …, W Cheng, J Yu. The genetic architecture of human amygdala volumes and their overlap with common brain disorders. Translational Psychiatry, [2023], 1-12. [PDF]

2022

(*) Y Li, BJ Sahakian, J Kang, C Langley, W Zhang, …, W Cheng, JF Feng. The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health. Nature Aging, [2022], 2(5), 425-437. [PDF]
(*) S Huang, Y Li, Y Zhang, Y Huang, …, W Cheng, JT Yu. Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants. Molecular Psychiatry, [2022]. [PDF]
(*) Z Wan, ET Rolls, J Feng, W Cheng. Brain functional connectivities that mediate the association between childhood traumatic events, and adult mental health and cognition. EBioMedicine, [2022], 79, 104002. [PDF]
(*) J You, YR Zhang, HF Wang, M Yang, JF Feng, JT Yu, W Cheng. Development of a novel dementia risk prediction model in the general population: A large, longitudinal, population-based machine-learning study. eClinicalMedicine, [2022], 53, 101665. [PDF]
(*) L Yang, YT Deng, Y Leng, YN Ou, YZ Li, …, W Cheng, JT Yu. Depression, Depression Treatments, and Risk of Incident Dementia: A Prospective Cohort Study of 354,313 Participants. Biological Psychiatry, [2022]. [PDF]
(*) J Du, ET Rolls, W Gong, M Cao, D Vatansever, J Zhang, J Kang, W Cheng, JF Feng. Association between parental age, brain structure, and behavioral and cognitive problems in children. Molecular Psychiatry, [2022], 27(2), 967-975. [PDF]
(*) Q Ma, H Wang, ET Rolls, S Xiang, J Li, Y Li, Q Zhou, W Cheng, F Li. Lower gestational age is associated with lower cortical volume and cognitive and educational performance in adolescence. BMC Medicine , [2022]. [PDF]
(*) L Wang, P Wu, P Brown, W Zhang, F Liu, et al. Association of Structural Measurements of Brain Reserve With Motor Progression in Patients With Parkinson Disease. Neurology, [2022]. [PDF]
(*) HF Wang, W Zhang, ET Rolls, Y Li, L Wang, …, W Cheng. Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology. EBioMedicine, [2022]. [PDF]
(*) L Wang, C Zhou, W Cheng, ET Rolls, P Huang, et al. Dopamine depletion and subcortical dysfunction disrupt cortical synchronization and metastability affecting cognitive function in Parkinson’s disease. Human Brain Mapping, [2022], 43(5), 1598-1610. [PDF]
(*) Q Ma, ET Rolls, CC Huang, W Cheng, J Feng. Extensive cortical functional connectivity of the human hippocampal memory system. Cortex, [2022], 147, 83-101. [PDF]
(*) YT Deng, YZ Li, SY Huang, YN Ou, W Zhang, …, W Cheng, JT Yu. Association of life course adiposity with risk of incident dementia: a prospective cohort study of 322,336 participants. Molecular Psychiatry, [2022]. [PDF]
(*) A Yang, ET Rolls, G Dong, J Du, Y Li, J Feng, W Cheng, XM Zhao. Longer screen time utilization is associated with the polygenic risk for Attention-deficit/hyperactivity disorder with mediation by brain white matter microstructure. EBioMedicine, [2022], 80, 104039. [PDF]
(*) L Wang, W Zhang, F Liu, C Mao, CF Liu, W Cheng, J Feng. Association of Cerebrospinal Fluid Neurofilament Heavy Protein Levels With Clinical Progression in Patients With Parkinson Disease. JAMA Network Open, [2022], 5(7), e2223821-e2223821. [PDF]

2021

(*) W Gong, ET Rolls, J Du, J Feng, W Cheng. Brain structure is linked to the association between family environment and behavioral problems in children in the ABCD study. Nature Communications, [2021], 12 (1):1-10. [PDF]
(#) L He, D Wei, F Yang, J Zhang, W Cheng, J Feng, W Yang, K Zhuang, et al. Functional connectome prediction of anxiety related to the COVID-19 pandemic. American Journal of Psychiatry, [2021], 178 (6), 530-540. [PDF]

2020

(#, *) LB Wang, W Cheng, ET Rolls, FL Dai, et al. Association of specific biotypes in patients with Parkinson disease and disease progression. Neurology, [2020]. [PDF]
(*) H Wang, ET Rolls, XJ Du, … W Cheng, JF Feng. Severe nausea and vomiting in pregnancy: psychiatric and cognitive problems, and brain structure in children. BMC Medicine, [2020]. [PDF]
(#, *) W Cheng, E Rolls, W Gong, J Du, J Zhang, XY Zhang, F Li, J Feng. Sleep duration, brain structure, and psychiatric and cognitive problems in children. Molecular Psychiatry, [2020]. [PDF]
(#, *) J Du, ET Rolls, W Cheng, Y Li, W Gong, J Qiu, J Feng. Functional connectivity of the orbitofrontal cortex, anterior cingulate cortex, and inferior frontal gyrus in humans. Cortex, [2020]: 123, 185-199. [PDF]
(#) ET Rolls, Y Zhou, W Cheng, M Gilson, G Deco, J Feng. Effective connectivity in autism. Autism Research, [2020]: 13 (1), 32-44. [PDF]

2019

(#, *) ET Rolls, W Cheng, J Du, D Wei, J Qiu, D Dai, Q Zhou, P Xie, J Feng. Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression. Social cognitive and affective neuroscience, [2019]. [PDF]
(#, *) ET Rolls, W Cheng, M Gilson, W Gong, G Deco, C Yo, et al. Beyond the disconnectivity hypothesis of schizophrenia. Cerebral Cortex, [2019], bhz161. [PDF]
Z Liu, ET Rolls, Z Liu, K Zhang, M Yang, J Du, W Gong, W Cheng, F Dai, et al. Brain annotation toolbox: exploring the functional and genetic associations of neuroimaging results. Bioinformatics, [2019]. [PDF]
W Cheng, ET Rolls, TW Robbins, W Gong, Z Liu, et al. Decreased brain connectivity in smoking contrasts with increased connectivity in drinking. eLife, [2019]. (eLife Digest) [PDF]

2018

W Cheng, ET Rolls, J Qiu, D Yang, H Ruan, D Wei, L Zhao, et al. Functional connectivity of the precuneus in unmedicated patients with depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, [2018]: 1040-1049. [PDF]
(#, *) ET Rolls, W Cheng, W Gong, J Qiu, C Zhou, J Zhang, et al. Functional connectivity of the anterior cingulate cortex in depression and in health. Cerebral Cortex, [2018]: 14. [PDF]
W Cheng, ET Rolls, H Ruan, J Feng, et al. Functional connectivities in the brain that mediate the association between depressive problems and sleep quality. JAMA Psychiatry, [2018], 75(10): 1052-1061. [PDF]
Z Liu, J Zhang, K Zhang, J Zhang, X Li, W Cheng, M Li, L Zhao, et al. Distinguishable brain networks relate disease susceptibility to symptom expression in schizophrenia. Human Brain Mapping, [2018], 39(9): 3503-3515. [PDF]
W Gong, L Wan, W Lu, L Ma, F Cheng, W Cheng, S Gruenewald, J Feng. Statistical testing and power analysis for brain-wide association study. Medical Image Analysis,[2018], 47: 15-30. [PDF]
W Cheng, ET Rolls, J Qiu, X Xie, W Lyu, Y Li, CC Huang, AC Yang, et al. Functional connectivity of the human amygdala in health and in depression. Social Cognitive and Affective Neuroscience, [2018], 13(6): 557-568. [PDF]
W Cheng, ET Rolls, J Qiu, X Xie, D Wei, CC Huang, AC Yang, SJ Tsai, et al. Increased functional connectivity of the posterior cingulate cortex with the lateral orbitofrontal cortex in depression. Translational Psychiatry, [2018], 8(1): 90. [PDF]
(#) ET Rolls, W Cheng, M Gilson, J Qiu, Z Hu, H Ruan, Y Li, CC Huang, et al. Effective connectivity in depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, [2018], 3(2): 187-197. (Cover Paper) [PDF]

2017

T Li, Q Wang, J Zhang, ET Rolls, W Yang, L Palaniyappan, L Zhang, W Cheng, et al. Brain-wide analysis of functional connectivity in first-episode and chronic stages of schizophrenia. Schizophrenia Bulletin, [2017], 43(2): 436-448. [PDF]
W Cheng, ET Rolls, J Zhang, W Sheng, L Ma, L Wan, Q Luo, J Feng. Functional connectivity decreases in autism in emotion, self, and face circuits identified by Knowledge-based Enrichment Analysis. NeuroImage, [2017], 148: 169-178. [PDF]

2016

W Cheng, ET Rolls, J Qiu, W Liu, Y Tang, CC Huang, XF Wang, J Zhang,, et al. Medial reward and lateral non-reward orbitofrontal cortex circuits change in opposite directions in depression. Brain, [2016], 139(12): 3296-3309. [PDF]
(#) J Zhang, W Cheng, Z Liu, K Zhang, X Lei, Y Yao, B Becker, Y Liu,, et al. Neural, electrophysiological and anatomical basis of brain-network variability and its characteristic changes in mental disorders. Brain, [2016], 139(8): 2307-2321. (Cover Paper) [PDF]
(#) Q Wang, W Cheng, M Li, H Ren, X Hu, W Deng, X Ma, L Zhao, et al. The CHRM3 gene is implicated in abnormal thalamo-orbital frontal cortex functional connectivity in first-episode treatment-naive patients with schizophrenia. Psychological Medicine, [2016], 46(7): 1523-1534. [PDF]
H Cui, J Zhang, Y Liu, Q Li, H Li, L Zhang, Q Hu, W Cheng, et al. Differential alterations of resting‐state functional connectivity in generalized anxiety disorder and panic disorder. Human Brain Mapping, [2016], 37(4): 1459-1473. [PDF]

2015

W Cheng, ET Rolls, H Gu, J Zhang, J Feng. Autism: reduced connectivity between cortical areas involved in face expression, theory of mind, and the sense of self. Brain, [2015], 138(5): 1382-1393. (Editor’s Choice) [PDF]
W Cheng, L Palaniyappan, M Li, KM Kendrick, J Zhang, Q Luo, Z Liu, et al. Voxel-based, brain-wide association study of aberrant functional connectivity in schizophrenia implicates thalamocortical circuitry. npj Schizophrenia, [2015], 1: 15016. (Editor’s Choice) [PDF]

2013

(#) Q Luo, W Lu, W Cheng, PA Valdes-Sosa, X Wen, M Ding, J Feng. Spatio-temporal Granger causality: A new framework. NeuroImage, [2013], 79: 241-263. [PDF]

2012

W Cheng, X Ji, J Zhang, J Feng. Individual classification of ADHD patients by integrating multiscale neuroimaging markers and advanced pattern recognition techniques. Frontiers in Systems Neuroscience, [2012] 6, 58. [PDF]
(#) J Zhang, W Cheng, ZG Wang, ZQ Zhang, WL Lu, GM Lu, J Feng. Pattern classification of large-scale functional brain networks: identification of informative neuroimaging markers for epilepsy. PloS one, [2012] 7 (5), e36733. [PDF]